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Hoffman was born to a Jewish family in Houston, TX, he lived most of his childhood in Lexington, Kentucky; attending Henry Clay High School. He attended Columbia University, where he studied writing and music production, and subsequently worked in the field of dance music. He had previously met Jake Shears - then still known as Jason Sellards - through a childhood friend, and Hoffman asked Shears to provide vocals for his tracks. When Hoffman moved to New York to study writing at Columbia, the duo officially joined forces and took stage names to become the first two members of Scissor Sisters in 2001. At the time, the band was just a combination of Babydaddy’s music and Jake’s vocal and visual performances. The band logo was designed by Babydaddy, who has since said that "it was sort of the first couple of days, and we decided to record music, and Jake had the name on the tip of his tongue. He told it to me, and I made the logo the next day. It was sort of done and made sense. And then we performed."
Babydaddy is considered a bear by many members of the gay community due to his husky frame, beard and friendly demeanor. He unwittingly became a sex-symbol for other bear admirers after the launch of the Scissor Sisters' first album Scissor Sisters. He has even acknowledged this status by stating "Jake gets a lot of attention just by virtue of being the lead singer, but when the boys want a little beef, they come to me."
Since then, the band has grown and recruited further members, in the process expanding its original musical style to cover the rock, disco and dance music genres.
Babydaddy plays a number of instruments including keyboards, guitar, bass and banjo; he and Shears are the main lyricists for the band. The two also wrote the hit single "I Believe In You" for Kylie Minogue, as well as the title track from her documentary White Diamond. Babydaddy has also co-produced with other artists including Tiga and Xavier and has produced remixes (alongside Jake Shears under the Scissor Sisters moniker) for Pet Shop Boys, The Ones and Blondie.
In 2010, Babydaddy remixed disco icon Amanda Lear's new single I'm Coming Up.